Table 1.
Phosphatidylinositol-3 kinase genes and proteins
| Class | Gene | Chromosomal location | Protein | Mass (kDa) | Sequence length (AA) |
|---|---|---|---|---|---|
| Class I |
|
|
|
|
|
| IA |
PIK3CA |
3q26.3 |
p110-α |
124.28 |
1068 |
| |
PIK3CB |
3q22.3 |
p110-β |
122.76 |
1070 |
| |
PIK3CD |
1p36.2 |
p110-δ |
119.48 |
1044 |
| |
PIK3R1 |
5q13.1 |
p85-α |
83.60 |
724 |
| |
PIK3R2 |
19p13.1 |
p85-β |
81.55 |
728 |
| |
PIK3R3 |
1p34.1 |
p55-γ |
54.45 |
461 |
| IB |
|
|
|
|
|
| |
PIK3CG |
7q22.3 |
π110-γ |
126.45 |
1102 |
| |
PIK3R5 |
17p13.1 |
p101 |
97.35 |
880 |
| |
PIK3R6 |
17p13.1 |
p84/p87PIKAP |
84.26 |
754 |
| Class II |
|
|
|
|
|
| |
PIK3C2A |
11p15.1 |
PIK-C2α |
190.68 |
1686 |
| |
PIK3C2B |
1q32.1 |
PIK-C2β |
184.77 |
1634 |
| |
PIK3C2G |
12p12.3 |
PIK-C2γ |
165.72 |
1445 |
| Class III |
|
|
|
|
|
| |
PIK3C3 |
18q12.3 |
hVps34 |
101.55 |
887 |
| PIK3R4 | 3q22.1 | p150 | 153.10 | 1358 |
Abbreviations: AA amino acids; kDa kilodalton.