Table II.

RMSD of C-Terminal Core Domains Within and Between a MAPK Families

MAPK	C-terminal core	Moving PDB	RMSD (Å2)	MAPK residues	ERK2 (3TEI) residues	RMSD (Å2)
ERK2 (3TEI)	108–173	2FYSa	1.04
	190–201	2GPHa	0.60
	207–254	3O71a	0.59
	258–326	2Y9Q	0.96
		4FMQ	1.04
		4H3Q	0.57
		4H3P	0.58
		4IZ5	0.60
p38 (2Y80)	109–117	1LEW	0.30	109–113	108–112
	123–171	1LEZ	0.40	123–169	122–168	0.65
	185–321	2OKR	0.31	298–315	303–320
		3P4K	0.38
		4KA3	0.40
		3TGI	1.10
JNK1 (2XRW)	111–170	1UKH	0.51	111–115	108–112
	199–250	2XS0	0.52	125–170	123–168	1.12
	267–281			311–328	303–320
	288–334
JNK3 (4H39)	149–207	4H3B	0.48	149–153	108–112
	222–319	4H36	0.55	163–208	123–168	1.02
	326–371			349–366	303–320
FUS3 (2B9H)	96–163	2B9I	0.37	98–100	110–112
	180–319	2B9J	0.24	111–156	123–168	0.46
				299–316	303–320
ERK5 (4IC7)	140–143	n/ab	n/ab	140–143	108–111
	156–199			156–199	123–166	0.54
	319–346			319–346	285–312

^aMouse/rat ERK2 isoform; C-terminal core residues corresponding to the human isoform are 106–171, 188–199, 205–252, 256–324.

^bOnly 1 ERK5 complex available.