Table II.
The Rates of Kinetic Steps of Actomyosin ATPase Cycle With Metal.Nucleotide as a Ligand
| Cation | Ionic radius, Angstroms | Coordination number | Actin binding to myosin.ADP, µM−1 s−1 | ATP induced actomyosin.ADP dissociation, µM | ATP induced actomyosin dissociation, µM−1 s−1 |
|---|---|---|---|---|---|
| Mg2+ | 0.72 | 6 | 1.69 ± 0.13 | 16.7 ± 1.9 | 1.64 ± 0.16 |
| Mn2+ | 0.83 | 6 | 1.29 ± 0.39 | 11.2 ± 1.6 | 1.71 ± 0.29 |
| Ca2+ | 1.0 | 7 | 1.61 ± 0.26 | 34.1 ± 3.7 | 0.35 ± 0.01 |