Table 3.

Compliance with index medication among matched cohorts

	Duloxetine	SOC
Compliance with index medication
Mean MPR (SD)	0.78 (0.25)	0.60 (0.32)*
MPR ≥0.8 (%)	60.8	35.8*
Mean PDC (SD)	0.50 (0.31)	0.31 (0.28)*
PDC ≥0.8 (%)	25.6	10.5*
Number of days on medication	92.9 (56.0)	54.8 (49.8)
Discontinuation (%)	56.7	79.7*

Notes:

^*Statistically significant at P < 0.05 (reference: duloxetine). SOC included gabapentin, pregabalin, venlafaxine, muscle relaxants, or tricyclic antidepressants.

Abbreviations: MPR, medication possession ratio; PDC, proportion of days covered; SD, standard deviation; SOC, standard of care.