Table 4.

Opioid use in the 6-month post-index period among matched cohorts

	Duloxetine	SOC
Opioid use (%)	45.1	60.7*
Long-acting opioids	4.2	7.0*
Short-acting opioids	44.3	59.9*
Days on opioid, median (25th, 75th percentile)	0 (0, 19)	7 (0, 30)*
Morphine equivalent dosage in milligrams, median (25th, 75th percentile)	0 (0, 510)	198 (0, 900)*

Notes:

^*Statistically significant at P < 0.05 (reference: duloxetine). SOC included gabapentin, pregabalin, venlafaxine, muscle relaxants, or tricyclic antidepressants.

Abbreviation: SOC, standard of care.