Table 1. Biomarkers of human vitreoretinal diseases.
| Human Biomarker Symbol | Description | Average Mouse Retina Peptide Hits | Average Mouse Vitreous Peptide Hits |
|---|---|---|---|
| C3 | Complement C3 | 1 | 0 |
| Capn1 | Calpain 1 | 1 | 0 |
| Capns1 | Calpain small subunit 1 | 8 | 0 |
| Capn2 | Calpain 2 | 2 | 0 |
| Car2 | Carbonic anhydrase II | 80 | 90 |
| Car3 | Carbonic anhydrase III | 1 | 21 |
| Cat | Catalase | 10 | 1 |
| Cryaa | Crystallins | 10,701 | 682 |
| Got1 | Glutamate oxaloacetate transaminase | 121 | 10 |
| Gpx4 | Glutathione peroxidase, nuclear | 10 | 6 |
| GST1 | Glutathione-S-Transferase | 9 | 4 |
| Mif | Macrophage migration inhibitory factor | 116 | 86 |
| Nos2 | Nitric oxide synthase 2 | 0 | 5 |
| PDGFr | Platelet derived growth factor receptor (alpha and beta) | 10 | 0 |
| PEDF | Pigment epithelium-derived factor | 0 | 0 |
| Prdx1 | Peroxiredoxin 1 | 100 | 8 |
| Prdx2 | Peroxiredoxin 2 | 122 | 14 |
| Prdx3 | Peroxiredoxin 3 | 14 | 0 |
| Prdx4 | Peroxiredoxin 4 | 38 | 2 |
| Prdx5 | Peroxiredoxin 5 | 123 | 87 |
| Prdx6 | Peroxiredoxin 6 | 76 | 32 |
| S100 | S100 precursors A6 and A11 | 39 | 21 |
| Sod1 | Superoxide dismutase [Cu-Zn] | 2 | 2 |
| VEGF | Vascular endothelial growth factor | 0 | 0 |
| vWF | Von willebrand factor precursor | 19 | 0 |
Peptide hits are listed for proteins found in mouse vitreous and/or retina.