Table 1.
Odds ratio R and steepness of dose-toxicity curve. The pair in each entry indicates the toxicity probabilities associated with the doses adjacent to the MTD, i.e., (pj−1,j, pj+1,j).
| θ |
R 1.25 |
1.50 | 1.75 | 2.00 | 2.25 | 2.50 |
|---|---|---|---|---|---|---|
| 0.10 | (0.08,0.12) | (0.07,0.14) | (0.06,0.16) | (0.05,0.18) | (0.05,0.20) | (0.04,0.22) |
| 0.15 | (0.12,0.18) | (0.11,0.21) | (0.09,0.24) | (0.08,0.26) | (0.07,0.28) | (0.07,0.31) |
| 0.20 | (0.17,0.24) | (0.14,0.27) | (0.13,0.30) | (0.11,0.33) | (0.10,0.36) | (0.09,0.38) |
| 0.25 | (0.21,0.29) | (0.18,0.33) | (0.16,0.37) | (0.14,0.40) | (0.13,0.43) | (0.12,0.45) |
| 0.30 | (0.26,0.35) | (0.22,0.39) | (0.20,0.43) | (0.18,0.46) | (0.16,0.49) | (0.15,0.52) |