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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Cancer Metastasis Rev. 2013 Dec;32(0):10.1007/s10555-013-9441-9. doi: 10.1007/s10555-013-9441-9

Figure-4. Drug Exclusion Mechanisms of Exosomes (hypothesis).

Figure-4

Diagram showing intracellular exosomal packaging of chemical drugs and or their breakdown products (active forms). Such exosome residing drugs can be expelled by cells, resulting in diminished drug efficacy and this is a distinctly separate from other drug transport mechanism.