Table 1.
Mean arterial blood pressure (MAP) during baseline, first doxapram injection, and at 30 and 60 min post-doxapram or corresponding time points in control groups.
| Baseline | Injection 1 | 30 min | 60 min | |
|---|---|---|---|---|
| Intermittent doxapram | 94 ± 8 | 129 ± 11* | 96 ± 11 | 87 ± 11 |
| Single doxapram 2mg/kg | 106 ± 16 | 138 ± 19* | 109 ± 17 | 99 ± 14 |
| Single doxapram 6mg/kg | 101 ± 13 | 151 ± 7* | 99 ± 17 | 103 ± 11 |
| Vehicle injections | 112 ± 20 | 124 ± 21 | 108 ± 21 | 101 ± 21 |
| Time control | 102 ± 13 | 102 ± 11 | 95 ± 11 | 95 ± 12 |
different from baseline, 30 min and 60 min post-injection.