Table 2.
Mean partial pressure of arterial oxygen (PaO2), carbon dioxide (PaCO2), and pH during baseline and 60 min post-doxapram administration.
| Baseline | 60 min post-injection | |
|---|---|---|
| PaO2 (mmHg) | ||
| Intermittent doxapram | 133 ± 4 | 118 ± 10 |
| Single doxapram 2mg/kg | 142 ± 9 | 138 ± 7 |
| Single doxapram 6mg/kg | 134 ± 10 | 126 ± 9 |
| Vehicle injections | 141 ± 6 | 132 ± 3 |
| Time control | 145 ± 16 | 139 ± 13 |
| PaCO2 (mmHg) | ||
| Intermittent doxapram | 39 ± 2 | 38 ± 2 |
| Single doxapram 2mg/kg | 39 ± 3 | 39 ± 3 |
| Single doxapram 6mg/kg | 41 ± 1 | 42 ± 1 |
| Vehicle injections | 43 ± 3 | 45 ± 3 |
| Time control | 34 ± 4 | 36 ± 4 |
| pH | ||
| Intermittent doxapram | 7.30 ± 0.01 | 7.29 ± 0.01 |
| Single doxapram 2mg/kg | 7.32 ± 0.02 | 7.32 ± 0.02 |
| Single doxapram 6mg/kg | 7.31 ± 0.01 | 7.30 ± 0.02 |
| Vehicle injections | 7.30 ± 0.02 | 7.29 ± 0.02 |
| Time control | 7.34 ± 0.03 | 7.33 ± 0.01 |