Table 1.
Inhibition of the chymotryptic-like activity of purified human 20S proteasome by compounds 1–5.
| compound IC50(μM) |
|
|
|
|
|
|---|---|---|---|---|---|
| proteasome | 2.5 | 1.4 | >10 | >10 | >10 |
| NF-κB-luc | 2.5 | 4.6 | >10 | >10 | >10 |
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