. Author manuscript; available in PMC: 2014 Jul 25.

Published in final edited form as: J Med Chem. 2013 Jul 3;56(14):10.1021/jm400235r. doi: 10.1021/jm400235r

Table 4.

Inhibition of the chymotryptic-like activity of purified human 20S proteasome by compounds 37–49. Data are averages of a minimum of two independent experiments, each as a technical triplicate. Individual values and standard error of the means are listed in supplemental Table S2.

	R₄	IC₅₀ (μM)

37	H	1.97
38	Ac	2.17
39	Bz	1.44
40		0.63
41		0.58
42		0.53
43		1.08
44		0.91
45		1.22
46		0.30
47		0.54
48		0.37
49		0.13