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. Author manuscript; available in PMC: 2015 Jan 25.
Published in final edited form as: Mol Cell Endocrinol. 2013 Apr 4;382(1):10.1016/j.mce.2013.03.025. doi: 10.1016/j.mce.2013.03.025

Fig. 2.

Fig. 2

In silico analysis of leptin-cytokine interactions in breast cancer. (A) Interaction networks between leptin and proteins involved in breast cancer were analyzed using Pathway studio program (Ariadine Genomics, MD). Detailed description of relationships detected is included in the supplementary material, (S1). (B) Relationships between leptin and main inflammatory cytokines [IL-6, IL-1, interleukin 17, (IL-17), TNF-α, and transforming growth factor beta, (TGF-β)] were imported and analyzed in terms of breast cancer. Detailed description of interactions is shown in supplementary material (S2).