Table 3.
Baseline characteristics of study participants by GSTP1 105 genotype (N=582)
| Wildtype (GSTP1 lle105) N=270 |
Variant (GSTP1 Val105) N=312 |
|
|---|---|---|
| Age, median years [IQR]a | 68.0 [62.9,72.7] | 68.0 [63.0,72.4] |
| Education, n (%) | ||
| Never finished high school | 14 (5.2) | 20 (6.4) |
| High school graduate | 66 (24.4) | 93 (29.8) |
| Some college | 75 (27.8) | 79 (25.3) |
| College graduate | 115 (42.6) | 120 (38.5) |
| Smoking status, n (%) | ||
| Never | 75 (27.8) | 97 (31.1) |
| Former | 175 (64.8) | 199 (63.8) |
| Current | 20 (7.4) | 16(5.1) |
| Alcohol consumption, median g/day [IQR]a | 5.5 [0,17.6] | 5.2 [0,15.4] |
| History of diabetes, n (%) | 29(10.7) | 41 (13.1) |
| English as first language, n (%) | 241 (89.3) | 279 (89.4) |
| Computer experience , n (%) | 120 (44.4) | 127 (40.7) |
| Blood lead, median ug/g [IQR]a | 4 [3, 6] | 5 [3, 7] |
| Patella lead, median ug/g [IQR.]a,b | 25 [16,36] | 24 [17,37] |
| Tibia lead, median ug/g [IQR]a,b | 19 [13,27] | 20 [13,28] |
| Baseline MMSE score, median [IQR]a,c | 27 [26,28] | 27 [26,28] |
a
IQR: interquartile range.
b
Patella lead measures with uncertainty value >15 and tibia lead measures with uncertainty value >10 were excluded.
c
Highest possible MMSE score in our analysis was 29 due to deletion of the question “what county are we in?”.