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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Pain. 2013 Aug 6;154(12):10.1016/j.pain.2013.07.052. doi: 10.1016/j.pain.2013.07.052

Figure 6. NGF Protein is Upregulated in Non-Neuronal Tissues by a High-Fat Diet.

Figure 6

Quantification of nerve growth factor (NGF) in (A) sciatic nerve, (B) DRG, (C) gastrocnemius, and (D) hindpaw skin. NGF levels were below the limit of detection in the spinal cord. A high-fat diet caused an increase in NGF in the DRG (A), gastrocnemius muscle (B), and hindpaw skin. While it appears that exercise decreases NGF closer to baseline levels in high-fat diet mice in the DRG and gastrocnemius, the only place where there was a significant decline in NGF content from HF-Sed to HF-Ex was in the hindpaw skin. Data are presented as means±SEM where n=6-11 per group per tissue. *=p<0.05, **=p<0.01.