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Unfolding thermodynamic parameters of TC5b and its D-amino acid mutants, adapted from ref 8. Also listed are the folding and unfolding times of these peptides at 30 °C.
| Peptide | ΔHm (kcal mol−1) | ΔSm (cal mol−1 K−1) | ΔCp (cal mol−1 K−1) | Tm (°C) | τf (μs) | τu (μs) |
|---|---|---|---|---|---|---|
| TC5b | 12.9 | 40.4 | 72.1 | 45.9 | 3.0 | 7.6 |
| 5b-10GDA | 17.1 | 50.4 | 53.6 | 66.6 | 1.7 | 33.4 |
| 5b-10GDQ | 16.5 | 48.2 | 63.9 | 69.3 | 2.5 | 44.0 |
| 5b-10GDN | 15.8 | 47.8 | 91.6 | 56.4 | 3.7 | 25.5 |
