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. 2013 Nov 11;2013:578786. doi: 10.1155/2013/578786

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Copyright © 2013 Béla Dénes et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Analyses of secreted cytokines/chemokines. (a) Cytokines/chemikines synthesized by splenocytes of CFA (1 : 0), rVV-CTB::GAD + CFA (1 : 0), and rVV-CTB::GAD + CFA (1 : 10) treatment group and naive (PBS) mice. (b) 4-5 mice from each experimental groups were euthanized and the synthesis of cytokines and chemokines in GAD-activated splenocytes was analysed. Means ± standard errors are shown for 4-5 mice/groups. Differences between ages of the treated groups of mice compared to PBS are statistically significant (one-way Anova, P < 0.05). Differences between groups in blood glucose and data of percentage of insulitis are statistically insignificant (one-way Anova, P > 0.05).