Table 1.
Comparison of number of Otx2-IR cells in the SC between the control (C1–6) and PDGFR-β KO (K1–4) mice.
| SC subfield | Control | PDGFR-β KO | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of cells per section | No. of cells per section | |||||||||||||
| C1 | C2 | C3 | C4 | C5 | C6 | Mean ± SD | K1 | K2 | K3 | K4 | Mean ± SD | %Change | P value | |
| ZO | 224.8 | 214.0 | 246.2 | 203.8 | 223.3 | 234.8 | 224.5 ± 15.0 | 153.8 | 157.5 | 160.8 | 156.8 | 157.2 ± 2.9 | −30.0% | 0.001 |
| SGR | 378.8 | 358.7 | 376.0 | 401.0 | 391.8 | 454.2 | 393.4 ± 33.1 | 240.5 | 271.2 | 231.0 | 239.3 | 245.5 ± 17.6 | −37.6% | 0.001 |
| OP | 325.5 | 385.7 | 399.0 | 330.3 | 350.0 | 354.7 | 357.5 ± 29.5 | 269.3 | 280.0 | 247.5 | 261.0 | 264.5 ± 13.7 | −25.2% | 0.001 |
| IGR | 316.2 | 316.2 | 302.0 | 279.2 | 328.5 | 299.8 | 307.0 ± 17.2 | 214.7 | 229.0 | 220.7 | 216.7 | 220.3 ± 6.3 | −28.2% | 0.001 |
| DL | 189.8 | 168.8 | 258.2 | 159.2 | 268.7 | 272.3 | 219.5 ± 52.5 | 176.3 | 138.3 | 147.0 | 159.2 | 155.2 ± 16.5 | −29.3% | 0.048 |
For each layer of the SC, the mean numbers of cells per section in each animal are indicated. In each animal, 6 sections were examined. %Change and P value indicate %change from the control mice and statistical significance from the control mice (unpaired t-test) in each layer. ZO: zonal layer; SGR: superficial gray layer; OP: optic layer; IGR: intermediate gray layer; and DL: deep layer.