Table 4.
Comparison of CCO versus NexCO including subgroup analysis for patients with low MAP, low and high TDCO, low and high SVRI, and high dose norepinephrine or hypothermia.
|
|
|
Overall | Low MAP | Low TDCO | High TDCO | Low SVRI | High SVRI | Norepinephrine | Hypothermia |
|---|---|---|---|---|---|---|---|---|---|
| ≤70 mmHg | ≤4 L/min | ≥8 L/min | ≤1700 dyne·s·cm−5/m² | ≥3000 dyne·s·cm−5/m² | ≥0.3 µg/kg/min | ≤35°C | |||
| No. of patients | 45 | 19 | 9 | 18 | 29 | 6 | 11 | 22 | |
| No. of paired measurements | 135 | 50 | 27 | 51 | 104 | 22 | 44 | 63 | |
|
| |||||||||
| Mean TDCO | L/min | 6.4 | 5.9 | 3.8 | 7.8 | 7.0 | 4.5 | 6.4 | 6.3 |
|
| |||||||||
| R 2 | 0.71 | 0.87 | 0.1 | 0.73 | 0.81 | 0.78 | 0.94 | 0.67 | |
| P value | <0.001 | <0.001 | NS | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |
|
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| Bias | L/min | 0.2 | 0.4 | 0.0 | 0.6 | 0.4 | 0.0 | 0.0 | 0.0 |
| Precision | L/min | 1.2 | 0.9 | 1.4 | 1.1 | 1.0 | 1.2 | 0.5 | 1.3 |
| Lower LA | L/min | −2.1 | −1.4 | −2.7 | −1.7 | −1.6 | −2.4 | −1.1 | −2.7 |
| Upper LA | L/min | 2.5 | 2.2 | 2.7 | 2.8 | 2.3 | 2.3 | 1.0 | 2.6 |
|
| |||||||||
| Percentage error | % | 36 | 30 | 71 | 29 | 29 | 53 | 16 | 42 |
TDCO: thermodilution cardiac output.
R 2: Pearson correlation coefficient.
LA: limits of agreement.
MAP: mean arterial pressure.
SVRI: systemic vascular resistance index.