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Overall design of the entire research project ‘Youth with Extreme Obesity Study’ (YES). This figure gives an overview about the successive built up of the subprojects 1 to 4 as well as the longitudinal observational cohort study within YES. SP1, 2, 3, 4 = subproject 1, 2, 3, 4; RCT = randomized controlled trial; BS = bariatric surgery; mo = month/s; t0, 1, 2, 3, 4, 5 = timepoints for baseline and follow-up examinations.
