Table 6.
Risk factors for increased fasting plasma glucose (FPG) level in 1540 HIV subjects (normal = 952, increased FPG = 588) on ARV medication
| Characteristics |
Normal |
Hypertensive |
aOR |
95.0 C.I. for OR |
p-value | |
|---|---|---|---|---|---|---|
|
Mean ± S.D. |
Mean ± S.D. |
Lower | Upper | |||
| N (%) | N (%) | |||||
|
Age (year) |
|
|||||
| Mean ± SD |
42.79 ± 9.68 |
47.17 ± 9.56 |
1.048 |
1.036 |
1.059 |
0.001 |
|
Gender | ||||||
| Male |
751 (78.9) |
494 (84.0) |
1.00 |
|
|
|
| Female |
201 (21.1) |
94 (16.0) |
0.711 |
0.543 |
0.931 |
0.013 |
|
Hypertension | ||||||
| No |
754 (82.6) |
398 (70.8) |
1.00 |
|
|
|
| Yes |
159 (17.4) |
164 (29.2) |
1.954 |
1.522 |
2.508 |
0.001 |
|
b-Blocker |
|
|
|
|
|
|
| taking |
43 (4.5) |
44 (7.5) |
1.00 |
|
|
|
| Not Taking |
909 (95.5) |
544 (92.5) |
0.585 |
0.379 |
0.902 |
0.014 |
|
Anti-hyperglycaemic |
|
|
|
|
|
|
| Taking |
35 (3.7) |
111 (18.9) |
1.00 |
|
|
|
| Not taking |
917 (96.3) |
477 (81.1) |
0.164 |
0.110 |
0.244 |
0.001 |
|
Diabetes mellitus | ||||||
| Yes |
96 (10.1) |
149 (25.3) |
1.00 |
|
|
|
| No |
856 (89.9) |
439 (74.7) |
0.330 |
0.249 |
0.438 |
0.001 |
|
TG (mmol/l) |
2.25 ± 1.74 |
2.65 ± 1.82 |
1.130 |
1.066 |
1.199 |
0.001 |
| <5.17 |
432 (45.4) |
197 (33.6) |
1.00 |
|
|
|
| ≥5.17 |
519 (54.6) |
389 (66.4) |
1.644 |
1.327 |
2.035 |
0.001 |
|
Hepatitis |
|
|
|
|
|
|
| No |
857 (90.0) |
498 (84.7) |
1.00 |
|
|
|
| Yes | 95 (10.0) | 90 (15.3) | 1.630 | 1.197 | 2.220 | 0.002 |
Adjusted for age, gender, ethnicity, hypertension, diabetes mellitus, CD4, HIV RNA Load, TC, TG, LDL, HDL, alcohol consumption, smoking, liver disease, medication with agents including ARV (PI), b-blocker, anti-hyperglycemic. aOR Adjusted odds ratio.