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. 2013 Sep 4;14:78. doi: 10.1186/1471-2156-14-78

Table 6.

Conditional probabilities of parent-child dyad genotypes given the sampling scheme of using the affected child as a proband

Genotype
P(G, C ∣ D), G = M or F,
P(G, C ∣ D),
# Obs
ParentG CaseC complex version simplified version  
AA
AA
p4ψ2/R + 2p3qψ2/(2R)
p3ψ2/R
m1
Aa
2p3qψ1/(2R) + p2q2ψ1/R
p2qψ1/R
m2
 
AA
2p3qψ2/(2R) + 4p2q2ψ2/(4R)
p2qψ2/R
m3
Aa
Aa
2p3qψ1/(2R) + 4p2q2(2ψ1)/(4R) + 2pq3ψ1/(2R)
pqψ1/R
m4
 
aa
4p2q2/(4R) + 2pq3/(2R)
pq2/R
m5
aa
Aa
p2q2ψ1/R + 2pq3ψ1/(2R)
pq2ψ1/R
m6
aa
2pq3/(2R) + q4/R
q3/R
m7
Total   1 1 m

Abbreviation: Obs = Observation.