Table 2.
Biochemical data from patients dialysing against different dialysate calcium concentrations
| Dialysate calcium | 1.0 mmol/l | 1.25 mmol/l | 1.35 mmol/l | ≥ 1.5 mmol/l |
|---|---|---|---|---|
| Calcium |
2.3 ± 0.17 |
2.3 ± 0.17 |
2.25 ± 0.17 |
2.23 ± 0.16 |
| Calcium corr |
2.45 ± 0.17 |
2.47 ± 0.16 |
2.43 ± 0.15 |
2.40 ± 0.13 |
| Phosphate |
1.62 ± 0.43* |
1.48 ± 0.51* |
1.48 ± 0.48* |
1.08 ± 0.3 |
| Albumin g/l |
39.3 ± 3.3 |
41.1 ± 3.7*+ |
39.4 ± 4.2 |
38.1 ± 3.7 |
| ALP |
128(89–180) |
87(71–113) |
96(69–138) |
91(73–108) |
| PTH |
45(22–77)*+ |
31(15–51) |
24(13–52) |
16(10–26) |
| TChol |
3.8 ± 1.0 |
4.0 ± 0.17 |
4.0 ± 1.0 |
3.9 ± 1.0 |
| HDL |
1.23 ± 0.33 |
1.28 ± 0.40 |
1.31 ± 0.55 |
1.02 ± 0.38 |
| LDL |
1.86 ± 0.89 |
2.09 ± 0.80 |
2.07 ± 0.94 |
2.04 ± 0.84 |
| TG |
1.40(0.8-1.93) |
1.20(0.9-1.1) |
1.20(0.9-1.9) |
1.65(1.1-2.58) |
| Statin (%) |
48.2 |
59.3 |
61 |
61.9 |
| Calcium |
0(0–1.28)* |
1.5(0–1.5) |
1.0(0–3.0) |
1.0(0–3.0) |
| Sevelamer |
0(0–1.0)* |
0(0–0) |
0(0–0) |
0(0–0) |
| Lanthanum |
0(0–250) |
0(0–0) |
0(0–0) |
0(0–0) |
| Cinacalcet |
0(0–30)* |
0(0–0) |
0(0–0) |
0(0–0) |
| Calcitriol |
3(0.94-5.25) |
3(0.75-5.25) |
1.75(0.75-4.5) |
1.5(0.-3) |
| PTX (%) | 5.6 | 8.3 | 1.7 | 0 |
Data expressed in mmol/l unless otherwise stated. Calcium (measured calcium), calcium corrected for serum albumin (Calcium corr), alkaline phosphatase IU/L (ALP), parathyroid hormone pmol/l (PTH), total cholesterol (TChol), high density lipoprotein (HDL), low density lipoprotein (LDL), triglycerides (TG). Drug prescription: HMG CoA3reductase (statin), calcium carbonate (Calcium) g/day, sevelamer g/day, lanthanum carbonate (lanthanum) g/day, calcitriol (ug/wk), and cinacalcet mg/day, percentage patients with parathyroidectomy (PTX). Results expressed as percentage (%), mean ± SD, or median (interquartile range). Patients dialysing with dialysate calcium 1.5 mmol/l (n = 17) added to those dialysing using calcium 1.75 mmol/l (n = 4) summated due to low numbers. *p < 0.05 by Chi square analysis or anova with post hoc correction vs high dialysate calcium (≥1.5 mmol/l) and + p < 0.05 vs calcium dialysate 1.35 mmol/l.