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. 2013 Aug 30;13:133. doi: 10.1186/1471-230X-13-133

Table 5.

Effects of NAC on redox status in the plasma and colonic mucosa of AA-induced piglets

Items Control AA NAC
Plasma
 
 
 
MPO, U/ L
136 ± 12a
172 ± 24b
150 ± 24a
SOD, U/ mL
87.3 ± 30.2
82.0 ± 13.6
77.2 ± 11.8
CAT, U/ mL
4.58 ± 1.29
3.64 ± 1.03
6.50 ± 3.19
MDA, nmol/ mg protein
5.12 ± 0.51a
6.97 ± 1.24b
5.41 ± 1.02a
Colonic mucosa
 
 
 
MPO, U/g wet mucosa
0.071 ± 0.003a
0.095 ± 0.018b
0.063 ± 0.016a
SOD, U/mg protein
20.9 ± 1.4
18.5 ± 4.2
20.5 ± 6.0
CAT, U/mg protein
1.16 ± 0.12b
0.99 ± 0.17a
0.87 ± 0.16a
MDA, nmol/mg protein 0.33 ± 0.04a 0.58 ± 0.16b 0.41 ± 0.15a

Data are means ± SD, n = 6. Control = piglets fed the basal diet and received intrarectal administration of sterile saline; AA = piglets fed the basal diet and received intrarectal administration of acetic acid; NAC = piglets fed the basal diet supplemented with 500 mg/kg NAC and received intrarectal administration of acetic acid. a-b: Values within a row with different letters differ (P < 0.05).

MPO Myeloperoxidase, SOD superoxide dismutase, CAT catalase, MDA malondialdehyde.