Table 7.

Effects of NAC on EGFR, AR, TNF-α and TLR4 mRNA levels in the colonic mucosa

Items	Control	AA	NAC
EGFR	1.00 ± 0.29b	0.82 ± 0.19ab	0.61 ± 0.12a
AR	1.00 ± 0.17a	1.28 ± 0.20a	1.58 ± 0.17b
TNF-α	1.00 ± 0.16b	0.61 ± 0.16a	0.60 ± 0.11a
TLR4	1.00 ± 0.04	0.86 ± 0.34	0.71 ± 0.10

Data are means ± SD, n = 6. Control = piglets fed the basal diet and received intrarectal administration of sterile saline; AA = piglets fed the basal diet and received intrarectal administration of acetic acid; NAC = piglets fed the basal diet supplemented with 500 mg/kg NAC and received intrarectal administration of acetic acid. ^a-b: Values within a row with different letters differ (P < 0.05). EGFR = epidermal growth factor receptor; AR = amphiregulin; TNF-α = tumor necrosis factor-alpha; TLR4 = toll-like receptor 4.