Table 2.
Differences in birthweight and gestational age for offspring of mothers with and without hyperemesis gravidarum (N = 71,468)
| N = 71,468 | Mean |
Crude estimate |
Adjusted estimate |
Adjusted estimate |
Adjusted estimate |
|
|---|---|---|---|---|---|---|
| β [95% CI] | β [95% CI]* | β [95% CI]*** | β [95% CI]**** | |||
|
Birthweight |
|
|
|
|
|
|
| No hyperemesis (HG) |
70,654 |
3602 gram |
1 Reference |
1 Reference |
1 Reference |
1 Reference |
| HG |
814 |
3567 gram |
−34.46 (−72.84 - 3.93 ) |
−46.89 (−80.53 -13.26)** |
−47.57 (−79.92- -13.21)** |
−23.42 (−56.71- 9.86 )** |
|
Gestational age |
|
|
|
|
|
|
| No HG |
70,654 |
279.7 days |
1 Reference |
1 Reference |
1 Reference |
1 Reference |
| HG | 814 | 278.0 days | −1.68 (−2.53- -0.84 ) | −1.50 (−2.34- -0.67 ) | -1.38 (−2.21- -0.55) | -0.97 (−1.80- -0.15 ) |
*Adjusted for maternal age, parity, BMI, education and smoking habits.
**Additional adjustment for gestational age and induction.
***Additional adjustment for asthma, diabetes 1, thyroid disease, depression, anxiety, other psychological problems, anorexia, anaemia and vitamin B12 deficiency.
****Adjustment for maternal weight gain.