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. 2013 Sep 5;13:34. doi: 10.1186/1472-6823-13-34

Table 2.

Comparison of lymphocyte subpopulations in HT and HC

Lymphocyte subpopulation
 Healthy control (HC)
 Hashimoto’s thyroiditis (HT)
  Number Mean ± standard deviation (median; range) Number Mean ± standard deviation (median; range)
Lymphocytes absolute per μl
 70
 2508 ± 763 (2550; 960 – 4200)
 18
 1917 ± 659 (1794; 665 – 3264)***
Lymphocytes (% of white blood cells)
 70
 33.6 ± 10.9 (33.3; 15.0 – 62.0)
 18
 33.1 ± 12.5 (34.5; 15.0 – 54.0)
CD3+ (% of total lymphocytes)
 66
 68.3 ± 6.9 (68.0; 47.8 – 82.5)
 18
 68.8 ± 8.5 (69.2; 43.8 – 80.8)
CD4+ (% of total lymphocytes)
 66
 39.1 ± 6.9 (39.6; 25.8 – 51.1)
 18
 38.9 ± 7.1 (40.1; 21.5 – 51.6)
CD8+ (% of total lymphocytes)
 66
 27.8 ± 6.4 (26.5; 13.7 – 44.3)
 18
 24.1 ± 6.2 (23.3; 14.5 – 38.5)***
CD19+ (% of total lymphocytes)
 66
 16.1 ± 4.3 (15.3; 9.2 – 25.9)
 18
 18.6 ± 8.2 (16.1; 10.0 – 44.4)
CD3-CD16/56+ (% of total lymphocytes)
 66
 10.9 ± 5.9 (9.7; 3.8 – 33.7)
 17
 7.3 ± 3.5 (6.4; 3.3 – 15.0)
HLA-DR + (% of CD3+)
 66
 5.9 ± 2.8 (5.2; 1.8 – 12.4)
 18
 6.1 ± 2.5 (5.4; 2.4 – 11.3)
CD28- (% of CD4+)
 65
 1.5 ± 1.3 (1.3; 0.09 – 8.4)
 16
 1.1 ± 0.9 (0.9; 0.1 – 2.7)
CD28- (% of CD8+)
 66
 11.1 ± 13.7 (3.9; 0.15 – 61.7)
 17
 19.8 ± 13.3 (14.5; 4.8 – 52.3)***
CD45RO + (% of CD4+)
 31
 35.9 ± 12.9 (36.4; 1.4 – 59.4)
 17
 46.2 ± 12.9 (47.3; 23.2 – 74.7)**
CD45RO + (% of CD8+)
 31
 19.7 ± 10.6 (17.8; 0.07 – 48.3)
 17
 29.1 ± 13.2 (27.7; 11.9 – 57.8)***
CD45RA + CD62L + (% of CD4+)
 64
 61.1 ± 14.4 (60.9; 9.9 – 88.2)
 17
 54.4 ± 18.5 (53.6; 10.6 – 85.3)
CD45RA + CD62L + (% of CD8+)
 63
 61.6 ± 14.9 (64.2; 16.7 – 93.3)
 17
 51.9 ± 14.9 (55.3; 26.5 – 72.5)**
CD25 + CD62L + (% of CD4+) 64 22.8 ± 11.8 (20.8; 4.5 – 78.1) 17 23.6 ± 7.3 (21.5; 14.2 – 39.4)

Difference between HT and HC: *** p < 0.01, ** p < 0.02. Numbers of investigated samples from HC and HT are given in separate columns. For technical reasons not all parameters were investigated in all HC and HT.