Table 4.
Relative telomere length (RTL) and T cell receptor excision circles (TRECs)
|
Parameter |
Healthy control (HC) |
Hashimoto’s thyroiditis (HT) |
||
|---|---|---|---|---|
| Number | Mean ± standard deviation (median; range) | Number | Mean ± standard deviation (median; range) | |
|
RTL in CD4 + CD45RA+ |
59 |
1.5 ± 0.9 (1.0; 0.03 – 4.3) |
17 |
1.2 ± 0.4 (1.1; 0.7 – 2.0) |
|
RTL in CD8 + CD45RA+ |
20 |
1.4 ± 0.6 (1.4; 0.6 – 2.9) |
12 |
1.8 ± 2.9 (1.1; 0.08 – 9.4) |
|
TRECs/ 1000 CD4 + CD45RA+ |
11 |
2299 ± 205 (2278; 2105 – 2514) |
5 |
554 ± 248 (397; 133 – 730)*** |
| TRECs/ 1000 CD8 + CD45RA+ | 16 | 1206 ± 1633 (541; 164 – 2615) | 4 | 333 ± 140 (360; 90 – 575) |
Numbers of investigated samples from HC and HT are given in separate columns. For technical reasons, lymphocyte populations were not investigated in all HC and HT.
Difference between HT and HC: *** p < 0.01.