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Schematic configurations adopted by mFAS to position catalytic domains into the proximity of ACP domain for domain-domain interactions. (A) A full 180o swiveling of lower body relative to the upper body permits the ACP to crosstalk with KS-AT domains from both subunits. (B) a 25o rotation of the lower body against the upper body leads to the two states of the reaction chambers-open and closed. 215×157mm (300 × 300 DPI).
