Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Nov 5;28(45):11685–11694. doi: 10.1523/JNEUROSCI.3035-08.2008

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2008 Society for Neuroscience 0270-6474/08/2811685-10$15.00/0

PMC Copyright notice

Figure 3. — NR2D-containing extrasynaptic NMDARs are activated when glutamate uptake is inhibited. A, Traces showing no effect of 0.5 μm PPDA on control NMDAR-EPSCs. B, Traces showing no effect of 10 μm UBP141 on control NMDAR-EPSCs. C, Graph of NMDAR-EPSC amplitude during incubation with 0.5 μm PPDA (filled symbols; n = 9) and 10 μm UBP141 (open symbols; n = 4). D, Traces showing PPDA inhibition of the TBOA enhancement of NMDAR-EPSCs, inset illustrates EPSCs on an expanded timescale. E, Representative experiment showing the PPDA inhibition of the TBOA enhancement of NMDAR-EPSCs. F, Traces showing the UBP141 inhibition of the TBOA enhancement of NMDAR-EPSCs, inset illustrates EPSCs on an expanded timescale. G, Representative experiment showing the UBP141 inhibition of the TBOA enhancement of NMDAR-EPSCs. H, Bar graph illustrating mean percentage changes in NMDAR-EPSC properties with TBOA alone (n = 17), TBOA + PPDA (n = 5) and TBOA + UBP141 (n = 4). *p < 0.05, ANOVA plus post hoc Tukey's test.