Table 4. Long-term effect of surgical procedure and factors affecting global health and breast symptoms in breast cancer patient.

	Global health		Breast symptoms
	Beta (s.e.)	P	Beta (s.e.)	P
Constant	74 (6.4)	<0.0001	19.8 (6.4)	0.002
Follow-up		<0.0001a		<0.0001a
Before surgery	Reference
After surgery	−6.7 (1.5)	<0.0001	Reference
6 Months after surgery	−4 (1.4)	0.005	4.4 (1.4)	0.0012
12 Months after surgery	−1.2 (1.4)	0.4	0.9 (1.4)	0.52
72 Months after surgery	−5.3 (1.4)	0.0002	−1.1 (1.3)	0.41
Axillary dissection type		0.0726a		0.84a
ALND	Reference		Reference
SLNB	−1.8 (2.5)	0.48	−1.1 (2.4)	0.6323
SLNB+ALND	−6.4 (2.8)	0.02	0.3 (2.7)	0.9075
Tumour size		0.0371a
>20 mm	Reference
10–20 mm	3.4 (2.4)	0.16
⩽0 mm	7.2 (2.8)	0.01
Hormone status				0.03
Postmenopausal			Reference
Premenopausal			4.4 (2)

Abbreviations: ALND=axillary lymph node dissection; SLNB=sentinel lymph node biopsy; s.e.=standard error.

NB: Multivariable analyses were adjusted for hospitals, hormonal status, the Scarff Bloom and Richardson grade, treaments: the type of surgery, adjuvant chemotherapy, hormone therapy, the occurrence of lymphedema and tumour size.

^aOverall effect.