Table 2. Standardized Incidence Ratio (SIR) for pancreatic cancer among 39 442 individuals infected with hepatitis C virus (HCV) compared with the general population.
|
Pancreatic cancer |
||||
|---|---|---|---|---|
| Oa | Eb | SIR | 95% CI | |
|
Lag period after HCV notification | ||||
| ⩽6 Months | 4 | 0.8 | 5.3 | (1.4, 13.5) |
| >6 Months |
34 |
16.5 |
2.1 |
(1.4, 2.9) |
|
Sex-stratified analysisc | ||||
| Men | 23 | 11.5 | 2.0 | (1.3, 3.0) |
| Women |
11 |
5.0 |
2.2 |
(1.1, 3.9) |
|
HCV durationc,d | ||||
| ⩽20 Years | 10 | 5.4 | 1.9 | (0.9, 3.4) |
| > 20 Years |
24 |
11.1 |
2.2 |
(1.4, 3.2) |
|
Year of birthc | ||||
| Before 1960 | 31 | 15.5 | 2.0 | (1.4, 2.8) |
| From 1960 | 3 | 1.0 | 3.0 | (0.6, 8.8) |
Abbreviation: CI=confidence interval.
a
Observed number of pancreatic cancer cases.
b
Expected number of pancreatic cancer cases.
c
Excluding cases and observation-time during the first 6 months after HCV notification.
d
Estimated duration of HCV infection.