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. Author manuscript; available in PMC: 2014 Nov 15.
Published in final edited form as: Clin Cancer Res. 2013 Sep 17;19(22):10.1158/1078-0432.CCR-13-1675. doi: 10.1158/1078-0432.CCR-13-1675

Figure 2.

Figure 2

Dual siRNA-mediated knockdown of CDK4 and CDK6 inhibits neuroblastoma growth. (A) siRNA-mediated knockdown of both CDK4 and CDK6 expression significantly reduced neuroblastoma growth in a manner that correlated with MYCN status (p = 0.03). Cell viabilities are expressed as the percentage of NTC (non-targeting control). (B) Representative protein depletion of CDK4, CDK6, and pRBS780.