Figure 1. Effects of diosgenin on object recognition memory in normal mice.

(A) Diosgenin (10 μmol/kg, i.p.) or vehicle solution was administered for 7 days to mice (males, 6 weeks old). On administration day 5, an object recognition test was started. The preference indices of the training and test sessions are shown. (*p < 0.05, two-tailed paired t-test; n = 3–5 mice). (B) Diosgenin (10 μmol/kg, i.p.) or vehicle solution was administered for 5 days to mice (males, 6 weeks old). One hour after the last administration on administration day 5, an object recognition test was initiated. The preference indices of the training and test sessions are shown. (*p < 0.05, two-tailed paired t-test; n = 3–5 mice).