Table 2. μCT analysis of cortical bone of tibiae.
|
Age, gender |
|||||
|---|---|---|---|---|---|
| 3 months ♂ | 6 months ♂ | 3 months ♀ | 6 months ♀ | ||
| |
N: fl/fl, ΔOB/ΔOB |
8, 9 |
8, 8 |
6, 10 |
6, 12 |
| BV (mm3) | ARfl/fl | 0.24±0.007 | 0.26±0.007 | 0.24±0.005 | 0.23±0.006 |
| ARΔOB/ΔOB | 0.26±0.004 | 0.24±0.009 | 0.23±0.005 | 0.23±0.004 | |
| TV (mm3) | ARfl/fl | 0.48±0.01 | 0.50±0.02 | 0.42±0.01 | 0.39±0.01 |
| ARΔOB/ΔOB | 0.51±0.01 | 0.46±0.02 | 0.43±0.01 | 0.40±0.01 | |
| B.Pm (mm) | ARfl/fl | 13.33±0.53 | 12.95±0.32 | 11.27±0.24 | 10.34±0.27 |
| ARΔOB/ΔOB | 13.77±0.28 | 12.24±0.41 | 11.83±0.37 | 10.71±0.14 | |
| B.Ar (mm2) | ARfl/fl | 0.89±0.03 | 0.95±0.02 | 0.90±0.02 | 0.86±0.02 |
| ARΔOB/ΔOB | 0.95±0.02 | 0.89±0.03 | 0.86±0.02 | 0.86±0.01 | |
| Ec.Ar (mm2) | ARfl/fl | 0.86±0.02 | 0.90±0.04 | 0.64±0.03 | 0.57±0.02 |
| ARΔOB/ΔOB | 0.92±0.03 | 0.82±0.03 | 0.72±0.03 | 0.59±0.01 | |
| BMD (g cm−3) | ARfl/fl | 1.11±0.02 | 1.15±0.02 | 1.13±0.04 | 1.14±0.02 |
| ARΔOB/ΔOB | 1.17±0.03 | 1.17±0.02 | 1.09±0.02 | 1.14±0.02 | |
Abbreviations: AR, androgen receptor; BMD, bone mineral density; CT, computed tomography.
Analysis of the cortical bone of tibia with μCT. No differences were detected between the two genotypes within the same age group and a gender in BMD or in any of the volumetric (BV, TV) or two-dimensional (bone perimeter, B. Pm, bone area, B.Ar, and endocortical area, Ec.Ar) parameters analyzed. Data are represented as means±s.e.m.