Table 1.
Demographic and clinical data of the 25OHD study population
| African Americans with CD (n=52) |
Caucasians with CD (n=64) |
African American Controls (n=40) |
p-value | |
|---|---|---|---|---|
| Age | ||||
|
| ||||
| Median (25%-75%) |
17.0 (15.0-18.5) | 15.5 (13.0-18.0) | 11.0 (5.0-15.0) | 0.0901 <0.001 |
|
| ||||
| 25OHD (ng/mL) | ||||
|
| ||||
| Mean (95% CI) |
16.1 (14.5-17.9) | 22.3 (20.2-24.6) | 16.3 (14.4-18.4) | <0.0012 0.990 |
|
| ||||
| Gender – N (%) | ||||
|
| ||||
| Male | 32 (61.5) | 39 (60.9) | 15 (37.5) | 0.038 |
| Female | 20 (38.5) | 25 (39.1) | 25 (62.6) | |
|
| ||||
| BMI – N (%) | ||||
|
| ||||
| Underweight | 12 (23.1) | 6 (9.4) | - | 0.118 |
| Normal | 32 (61.5) | 44 (68.8) | - | |
| Overweight | 5 (9.6) | 10 (15.6) | - | |
|
| ||||
| CD Severity – N (%) | ||||
|
| ||||
| Non-complicated | 27 (51.9) | 43 (67.2) | - | 0.109 |
| Complicated | 21 (40.4) | 17 (26.6) | - | |
|
| ||||
| History of Surgery – N (%) | ||||
|
| ||||
| Yes | 9 (17.3) | 14 (21.9) | - | 0.642 |
| No | 43 (82.7) | 50 (78.1) | - | |
|
| ||||
| Seasonality – N (%) | ||||
|
| ||||
| Winter | 19 (36.5) | 23 (35.9) | 3 (7.5) | <0.001 |
| Spring | 15 (28.8) | 22 (34.4) | 8 (20.0) | |
| Summer | 8 (15.4) | 18 (28.1) | 19 (47.5) | |
| Fall | 10 (19.2) | 1 (1.6) | 10 (25.0) | |
1
25OHD values were not normally distributed. A log-transformation was applied prior to data analysis. The resulting means and confidence limits were then back-transformed to the original units (ng/mL).
2
p-values were calculated using Dunnett’s MCP test on log-transformed Vitamin D to account for non-normality. The first p-value is Underweight vs Normal. The second p-value is Underweight vs Overweight. The third p-value is Normal vs Overweight.
3
Spearman’s rank correlation and associated 95% confidence interval.