Table 1.
Treatment | Sample Size |
Mean Baseline(SD)* | Mean AGE (SD)** | # of Females** |
# of Males** |
---|---|---|---|---|---|
Olanzapine | 134 | 73.5 (18.8) | 40.5 (11.6) | 34 | 100 |
Quetiapine | 124 | 73.5 (18.0) | 40.5 (11.2) | 29 | 95 |
Risperidone | 134 | 77.5 (17.2) | 42.2 (11.4) | 29 | 105 |
Ziprasidone | 74 | 71.3 (16.2) | 40.1 (11.1) | 21 | 53 |
Baseline PANSS was a significant contributor to drug response and therefore was incorporated into the mixed model that provided the response variable used for the genetic analysis;
Both sex and age were considered for inclusion in the response model; however as they did not significantly contribute to response they were not included in the final mixed model.