Table 2.

Performance measures based on cross-validation (Multivariable Models)

Method (Model)	LOOCV AUC (95% CI)	LOOCV ACC	3CV AUC (95% CI)	3CV ACC (SD)
LR (with age, males only)	0.95 (0.93–0.98)	87.29	0.95 (0.91–0.99)	87.27 (4.02)
LR (without age, males only)	0.91 (0.86–0.95)	81.76	0.91 (0.87–0.96)	81.76 (4.27)
LR (with age, gender)	0.95 (0.92–0.97)	87.87	0.95 (0.91–0.98)	88.01 (3.11)
LR (without age, gender)	0.94 (0.91–0.97)	86.60	0.94 (0.91–0.97)	85.22 (3.06)
PLR (λ = 0.1) (male only, with age)	0.95 (0.93–0.98)	87.29	0.95 (0.92–0.99)	86.7 (3.39)
PLR (λ = 1) (male only, with age)	0.95 (0.93–0.98)	87.29	0.96 (0.92–0.99)	87.77 (8.36)
PLR (λ = 10) (male only, with age)	0.95 (0.92–0.98)	87.29	0.95 (0.91–0.99)	86.39 (3.90)
PLR (λ = 0.1) (male only, without age)	0.91 (0.87–0.95)	81.76	0.91 (0.86–0.96)	81.73 (4.31)
PLR (λ = 1) (male only, without age)	0.91 (0.87–0.90)	82.32	0.91 (0.85–0.96)	81.96 (4.40)
PLR (λ = 10) (male only, without age)	0.90 (0.86–0.94)	81.21	0.91 (0.85–0.96)	81.80 (4.41)
PLR (λ = 0.1) (gender, with age)	0.95 (0.92–0.97)	87.87	0.95 (0.92–0.98)	87.18 (3.07)
PLR (λ = 1) (gender, with age)	0.95 (0.92–0.98)	87.87	0.95 (0.92–0.98)	87.99 (2.72)
PLR (λ = 10) (gender, with age)	0.94 (0.92–0.97)	86.74	0.94 (0.91–0.98)	86.31 (3.07)
PLR (λ = 0.1) (gender,,without age)	0.92 (0.89–0.95)	84.46	0.92 (0.88–0.96)	84.09 (3.38)
PLR (λ = 1) (gender, without age)	0.92 (0.89–0.95)	84.09	0.92 (0.88–0.96)	84.41 (3.39)
PLR (λ = 10) (gender, without age)	0.92 (0.89–0.95)	84.09	0.92 (0.87–0.96)	83.85 (3.38)
CART (with age, male only)	0.82 (0.75–0.89)	83.42	0.83 (0.74–0.93)	81.52 (4.95)
CART (without age, male only)	0.76 (0.67–0.85)	84.53	0.81 (0.72–0.90)	79.27 (5.01)
CART (with age, gender)	0.87 (0.82–0.92)	82.19	0.87 (0.80–0.94)	81.91 (3.54)
CART (without age, gender)	0.81 (0.75–0.86)	79.54	0.86 (0.79–0.93)	83.55 (3.91)