Table 3.
Effect of methanol extract of Dalbergia sissoo bark on GSH, TBARSs, H2O2, and γ-GT in gastric tissues.
| Treatments | GSH (nM/mg tissue) | TBARSs (nM/mg protein) | H2O2 (nM/min/mg tissue) | γ-GT (U/mg protein) |
|---|---|---|---|---|
| Control | 76.8 ± 6.7* | 55.1 ± 4.5* | 0.90 ± 0.25* | 0.20 ± 0.07* |
| Diclofenac (50 mg) | 59.7 ± 6.2† | 71.0 ± 5.3† | 1.76 ± 0.50† | 0.44 ± 0.07† |
| Diclofenac + DSME (200 mg) | 65.7 ± 6.4† | 64.9 ± 4.2 | 1.34 ± 0.61*,† | 0.38 ± 0.09† |
| Diclofenac + DSME (400 mg) | 73.3 ± 5.9* | 60.9 ± 3.4* | 1.21 ± 0.12* | 0.31 ± 0.09*,† |
| DSME (400 mg) | 75.0 ± 5.2* | 54.9 ± 5.2* | 0.99 ± 0.32* | 0.25 ± 0.06* |
Data are presented as mean ± standard deviation (n = 6).
*Indicates significance at p < 0.05 from the diclofenac-treated group.
†Indicates significance at p < 0.05 from the control group.
DSME = D. sissoo stem bark methanol extract; GSH = glutathione; H2O2 = hydrogen peroxide; TBARSs = thiobarbituric acid reactive substances; γ-GT = gamma-glutamyl transpeptidase.