Table 1.

Dosing regimens

Cohort	n	Day 1	Day 2	Day 3
1	20	600 mg CQ	600 mg CQ + placebo TQ	300 mg CQ + placebo TQ
2	20	Placebo CQ	Placebo CQ + 450 mg TQ	Placebo CQ + 450 mg TQ
3	20	600 mg CQ	600 mg CQ + 450 mg TQ	300 mg CQ + 450 mg TQ

Abbreviations are as follows: CQ, chloroquine (as base); and TQ, tafenoquine.