Figure 5.

Once-daily (50 μg) and twice-daily (2 × 25 μg) dosing pharmacokinetic profile of glycopyrronium in lung and systemic compartments. LUNG represents the sum of the amounts of drug in the intermediate and slow lung absorption compartments. SYS represents the sum of the amounts of drug in the three pharmacokinetic compartments, V1, V2 and V3.
, inhaled twice daily;
, inhaled once daily