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. Author manuscript; available in PMC: 2013 Dec 2.
Published in final edited form as: J Immunol. 2009 Mar 15;182(6):10.4049/jimmunol.0803121. doi: 10.4049/jimmunol.0803121

FIGURE 6.

FIGURE 6

Calcineurin inhibition impairs immature anti-insulin B cell proliferation to anti-CD40 stimulation. 125Tg immature B cells were cultured without insulin for 1 day, then stimulated with anti-CD40 (x-axis) in the absence (□) or presence of 1 μg/ml cyclosporin A (■). [3H]Thymidine incorporation (cpm) was measured after 2 days. The average of triplicate determinations of four animals ± SD is shown; *, p < 0.021 and **, p < 0.0048, as calculated by a two-tailed, two-sample/unequal variance t test. Immature B cells were generated as in Fig. 2B.