Table 1.
Baseline Characteristics of Unresected Stage III Elderly NSCLC Cohort Treated with and Without Radiotherapy.
| Characteristic | Radiation Therapy (N=6,468) | No Treatment (N=3,908) |
P-value
|
|
|---|---|---|---|---|
| Unadjusted | Adjusted* | |||
| Age, years, n (%) | 0.07 | 0.7 | ||
| ≤69 | 1,619 (25) | 908 (23) | ||
| 70–75 | 2,167 (34) | 1,306 (33) | ||
| >75 | 2,682 (41) | 1,694 (44) | ||
| Female, n (%) | 2,534 (39) | 1,645 (42) | 0.003 | 0.9 |
| Race, n (%) | ||||
| White | 5,085 (78) | 2,983 (76) | 0.03 | 0.9 |
| African American | 650 (10) | 434 (11) | ||
| Hispanic | 291 (5) | 214 (6) | ||
| Other | 442 (7) | 277 (7) | ||
| Marital Status | ||||
| Married | 3,521 (54) | 1,985 (51) | 0.0003 | 0.9 |
| Estimated Median Income, n (%) | ||||
| Highest three quartiles | 4,786 (74) | 2,807 (72) | 0.04 | 0.9 |
| Lowest quartile | 1,682 (26) | 1,101 (28) | ||
| Tumor Location, n (%) | ||||
| Upper lobe | 3,823 (59) | 2,109 (54) | <0.0001 | 0.9 |
| Middle lobe | 222 (3) | 150 (4) | ||
| Lower lobe | 1,328 (21) | 903 (23) | ||
| Other | 1,095 (17) | 747 (19) | ||
| Tumor Size, (mm), n (%) | ||||
| ≤20 | 398 (6) | 443 (11) | <0.0001 | 0.9 |
| 21–30 | 680 (11) | 537 (14) | ||
| 31–50 | 1,645 (25) | 944 (24) | ||
| 51–70 | 1,098 (17) | 514 (13) | ||
| >70 | 820 (13) | 399 (10) | ||
| Unknown | 1,827 (28) | 1,071 (28) | ||
| Stage | ||||
| IIIA | 3,196 (49) | 1,942 (50) | 0.78 | 0.9 |
| IIIB | 3,272 (51) | 1,966 (50) | ||
| Histology, n (%) | ||||
| Adenocarcinoma | 1,866 (29) | 1,636 (41) | <0.0001 | 0.9 |
| Squamous cell carcinoma | 3,201 (49) | 1,472 (38) | ||
| Large cell carcinoma | 521 (8) | 267 (7) | ||
| Other | 880 (14) | 533 (14) | ||
| Charlson Comorbidity Score, n (%) | ||||
| <1 | 3,991 (62) | 2,214 (57) | <0.0001 | 0.9 |
| 1–2 | 1,344 (21) | 785 (20) | ||
| >2 | 1,133 (18) | 909 (23) | ||
*
Adjusted for propensity score