Table 2.
Characterizations of blood pressure variability and association with percent delta creatinine.
| BP descriptor | P value for BP measure | Model r-square | Hemodynamic variable median (25th–75th percentile) (units are indicated in the first column) |
|---|---|---|---|
| AUC for 95/135 (mm Hg·min) | 0.33 | 0.058 | 930 (424–2707) |
| AUC < 95 (mm Hg·min) | 0.36 | 0.058 | 447 (130–1584) |
| AUC > 135 (mm Hg·min) | 0.72 | 0.058 | 207 (71–443) |
| AUC for 20% (mm Hg·min-above + below) | 0.08 | 0.059 | 2268 (702–5698) |
| AUC for 20% below baseline | 0.09 | 0.059 | 2117 (509–5542) |
| AUC for 20% above baseline | 0.74 | 0.058 | 5.07 (0–74) |
| Number of total incursions | 0.31 | 0.058 | 13 (9–17) |
| Number of incursions >135 | 0.25 | 0.058 | 4 (2–6) |
| Number of incursions <95 | 0.57 | 0.058 | 9 (5–13) |
| Cumulative minutes >135 or <95 mm Hg (min) | 0.42 | 0.058 | 17.7 (3.1–6.8) |
| Minutes >135 or <95 mm Hg per incident (min) | 0.29 | 0.061 | 4.8 (3.3–7.8) |
| Cumulative minutes >135 mm Hg (min) | 0.39 | 0.058 | 14 (6–25) |
| Minutes >135 mm Hg per incursion (min) | 0.84 | 0.061 | 3.7 (2.3–5.7) |
| Cumulative minutes <95 mm Hg (min) | 0.55 | 0.058 | 49 (18–116) |
| Minutes <95 mm Hg per incursion (min) | 0.27 | 0.058 | 4.9 (2.8–10.8) |
| Mean incursion nadir <95 mm Hg | 0.01 | 0.060 | 13 (9–17) |
| Mean incursion peak >135 mm Hg | 0.56 | 0.058 | 21 (12–31) |
| Percent change below baseline (to minimum) | 0.006 | 0.065 | 53 (62–43) |
| Percent change above baseline (to maximum) | 0.51 | 0.063 | 24 (9–48) |
All models are adjusted for aprotinin use, age, chf, previous mi, baseline creatinine, bypass time, diabetes, weight, valve surgery, gender, and pulse pressure. P values for these covariates are not shown.