Table 1.
Patient profiles by types of dengue infection: dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS).
| Patient profiles | DF (n = 391) | DHF (n = 296) | DSS (n = 90) | P value* |
|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | ||
| Demographic | ||||
| Male (n, %) | 185 (47.3) | 153 (51.7) | 38 (42.2) | 0.888 |
| Age (year) | 9.5 ± 3.4 | 10.1 ± 3.1 | 9.0 ± 3.5 | 0.903 |
| Mode of presentation | ||||
| Hepatomegaly (n, %) | 8 (2.1) | 26 (8.8) | 55 (61.1) | <0.001 |
| Headache (n, %) | 228 (58.3) | 145 (49.0) | 35 (38.9) | <0.001 |
| Myalgia (n, %) | 84 (21.5) | 30 (10.1) | 12 (13.3) | 0.001 |
| Vomiting (n, %) | 244 (62.4) | 216 (73.0) | 56 (62.2) | 0.187 |
| Cough (n, %) | 120 (30.7) | 94 (31.8) | 32 (35.6) | 0.425 |
| Abdominal pain (n, %) | 160 (40.9) | 181 (61.2) | 60 (66.7) | <0.001 |
| Rash (n, %) | 166 (42.5) | 132 (44.6) | 26 (28.9) | 0.124 |
| Pleural effusion (n, %) | 0 (0) | 20 (6.8) | 34 (37.8) | <0.001 |
| Petechiae (n, %) | 27 (6.9) | 26 (8.8) | 14 (15.6) | 0.016 |
| Any bleeding episodes (n, %) | 73 (18.7) | 80 (27.0) | 51 (56.7) | <0.001 |
| Hemodynamic | ||||
| SBP (mmHg) | 97.0 ± 9.2 | 96.9 ± 10.1 | 91.3 ± 10.3 | <0.001 |
| DBP (mmHg) | 58.4 ± 7.7 | 58.2 ± 8.6 | 58.6 ± 8.4 | 0.084 |
| Pulse pressure (mmHg) | 33.1 ± 6.7 | 32.1 ± 7.6 | 24.0 ± 7.7 | <0.001 |
| Hematological | ||||
| Hematocrit (%) | 38.8 ± 4.5 | 40.5 ± 4.8 | 42.4 ± 5.4 | <0.001 |
| Hemoglobin (g/dL) | 12.7 ± 1.5 | 13.4 ± 1.5 | 14.1 ± 1.8 | <0.001 |
| White cell count (/µL) | 3748.0 ± 1706.5 | 4271.3 ± 1821.8 | 5479.3 ± 2063.4 | <0.001 |
| Lymphocytes (%) | 44.9 ± 17.3 | 40.8 ± 15.7 | 40.0 ± 16.3 | <0.001 |
| Neutrophils (%) | 44.7 ± 18.8 | 49.5 ± 18.1 | 48.9 ± 17.6 | <0.001 |
| Platelet (/µL) | 122693.6 ± 9763.9 | 81869.0 ± 7975.7 | 50481.5 ± 6262.9 | <0.001 |
| Biochemical | ||||
| AST (U/L) | 126.7 ± 313.7 | 269.0 ± 457.1 | 558.9 ± 659.0 | <0.001 |
| ALT (U/L) | 60.1 ± 216.1 | 95.0 ± 271.7 | 219.8 ± 413.2 | 0.001 |
| PT (sec) | 12.0 ± 1.5 | 12.1 ± 1.8 | 15.5 ± 9.5 | 0.012 |
| PTT (sec) | 30.4 ± 5.4 | 42.0 ± 10.0 | 44.7 ± 12.3 | 0.004 |
| Case management | ||||
| Inbound referral (n, %) | 43 (11.0) | 78 (26.4) | 48 (53.3) | <0.001 |
| Discharged | ||||
| Alive (n, %) | 391 (100.0) | 296 (100.0) | 88 (97.8) | 1.000 |
| Outbound referral (n, %) | 0 (0) | 0 (0) | 2 (2.2) | |
| In hospital dead (n, %) | 0 (0) | 0 (0) | 0 (0) |
*P value from nonparametric test for trend.
SD: standard deviation; SBP: systolic blood pressure; DBP: diastolic blood pressure; AST: aspartate aminotransferase; ALT: alanine aminotransferase; PT: prothrombin time; PTT: partial thromboplastin time.