Table 1. Baseline and treatment characteristics of 39 patients with non-small cell lung cancer.
Category | Item | Number |
Age (years; median, range) | 66 (45-87) | |
Duration (days; median, range) | First TKI | 79 (10-639) |
All TKI | 125 (10-899) | |
Gender | Men | 18 |
Women | 21 | |
Active mutation | Exon 19 | 19 |
Exon 21 | 17 | |
Exon 18 | 3 | |
Stage | IIIB | 8 |
IV | 23 | |
postoperative recurrence | 8 | |
Histopathology | Adenocarcinoma | 36 |
Adeno-squamous carcinoma | 1 | |
Squamous cell carcinoma | 2 | |
First-line chemotherapy | Cytotoxic | 26 |
TKI | 13 | |
Response to first chemotherapy | PR | 14 |
SD | 9 | |
PD | 5 | |
(TKI alone) | (11) | |
First TKI | Gefitinib | 30 |
Erlotinib | 9 | |
First TKI response | PR | 19 |
PD | 13 | |
NE | 7 | |
Re-challenge TKI | Yes | 15 |
No | 24 |
TKI, tyrosine kinase inhibitor; PR, partial response; SD, stable disease; PD, progressive disease; NE, not evaluated.