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. 2013 Oct 24;5(11):2141–2154. doi: 10.1093/gbe/evt163

Table 1.

Primate TRIM Genes Evolving Under Positive Selection

TRIM Gene M7vsM8 (2lnλ) P Value % of Positively Selected Sites Average dN/dS for Selected Sites Positively Selected Sites No. of Primate Taxa
TRIM2 7.31 0.026 0.64 1.54 98, 497 12
TRIML2 6.03062 0.049 3.63 8.74 277 8
TRIM5 73.47 <0.005 20.46 3.29 7, 139, 175, 182, 213, 215, 228, 257, 258, 310, 311, 317, 324, 379, 381, 382, 418, 421, 423, 471, 483 22
TRIM7 9.92 0.007 0.36 11.04 258 10
TRIM10 6.06 0.048 2.00 3.62 152, 329 11
TRIM15 10.74 <0.005 5.86 2.25 18, 42, 150, 460 11
TRIM21 7.02 0.03 3.38 4.81 124, 407 10
TRIM22 10.20 <0.005 4.89 6.17 99, 171, 220, 308 13
TRIM25 19.27 <0.005 9.39 2.40 58, 259, 297, 338, 377, 415, 418, 420, 435 10
TRIM31 15.06 <0.005 5.27 8.68 72, 227, 250 7
TRIM38 6.51 0.039 3.66 2.94 215 12
TRIM52 16.51 <0.005 6.66 5.84 75, 111, 149, 153, 221 7
TRIM58 17.75 <0.005 4.24 2.34 223, 443, 472, 475, 480 10
TRIM60 8.00 0.018 20.43 2.15 8, 82, 96, 134, 200, 251, 252, 255, 264, 271, 302, 322, 370, 405, 459 11
TRIM69 6.65 0.036 19.16 2.46 14, 158, 192, 226, 246, 261, 285, 353, 371, 473 10
TRIM75 10.61 <0.005 0.67 12.24 45, 227 10
TRIM76 42.29 <0.005 1.71 7.94 306, 651, 1507, 2727, 2797, 3314 10

Note.—PAML model M7 (Ns sites model disallowing positive selection) was directly compared with M8 (Ns sites model permitting one extra category of codons evolving under positive selection) to detect positive selection (Yang 2007). We indicate the category of codons that were found to be in the category of positively selected codons and the average dN/dS associated with those codons. Sites underlined were also found to be under positive selection by Datamonkey (Delport et al. 2010).