Influence of shear on the graft geometry with inclusion of an active lumen area - shear feedback loop and excluding the effect of wall tension (A – B), with an active lumen area - shear feedback loop and the inclusion of smooth muscle cell migration from the media to intima (C – D), and with an active lumen area - shear feedback loop and the inclusion of extracellular matrix production and smooth muscle cell production in response to altered wall tension (E – F). Compartment/layer thickness (A, C, E) and graft radius (B, D, F).