Table 5.

Phenotypic (ρ_P), genetic (ρ_G), and environmental (ρ_E) correlations between number of MS components (MSC-N) and measures of obesity and body composition, insulin resistance and insulin secretion, inflammation, acanthosis nigricans and physical fitness, among SAFARI children and adolescents, aged 6 to 17 years old, without diabetes

Trait Paira	ρP	P value	ρG ± SE	P value	ρE ± SE	P value
MSC-N: Overweight	0.66	5.2 × 10−37	0.83 ± 0.13	6.5 × 10−6	0.49 ± 0.30	0.2261
MSC-N: Obese	0.73	4.6 ×10−49	0.84 ± 0.11	1.5 × 10−5	0.59 ± 0.22	0.0711
MSC-N: Fat massb	0.64	6.7 × 10−52	0.73 ± 0.11	3.3 × 10−5	0.54 ± 0.15	0.0183
MSC-N: Lean massc	0.46	5.6 × 10−27	0.58 ± 0.13	0.0009	0.31 ± 0.17	0.1263
MSC-N: %Body fat	0.60	9.0 × 10−44	0.58 ± 0.11	0.0003	0.67 ± 0.15	0.0091
MSC-N: HOMA-IRc	0.56	5.7 × 10−42	0.60 ± 0.11	0.0007	0.51 ± 0.14	0.0180
MSC-N: Matsuda ISIc	−0.56	1.5 × 10−28	−0.58 ± .015	0.0060	−0.53 ± 0.16	0.0176
MSC-N: Insulinogenic indexc	0.32	7.5 × 10−10	0.41 ± 0.19	0.0499	0.20 ± 0.23	0.4057
MSC-N: C-peptidec	0.32	1.0 × 10−11	0.49 ± 0.15	0.0055	0.04 ± 0.26	0.8937
MSC-N – hs-CRPc	0.37	1.6 × 10−17	0.59 ± 0.17	0.0082	0.22 ± 0.14	0.1761
MSC-N: AN-SS	0.46	3.4 × 10−26	0.54 ± 0.14	0.0007	0.37 ± 0.21	0.1267
MSC-N: Harvard PFS	−0.26	2.9 × 10−8	−0.45 ± 0.16	0.0063	0.06 ± 0.24	0.8078

^aAll traits were adjusted for the covariate effects as described in the text;

^bdata were log-transformed;

^cdata were transformed using inverse normal transformation.