Table 2.
Comparison of demographic conditions, spirometric values, and plasmatic values of Ig and IgG subclass in patients with and without asthma-associated bronchiectasis.
| Asthma-associated bronchiectasis (n = 12) |
Non-asthma-associated bronchiectasis (n = 88) |
P value | ||
|---|---|---|---|---|
| Baseline conditions | Age | 64.5 ± 8 | 56.4 ± 12.4 | <0.05 |
| Time from diagnosis (yr) | 30.14 ± 7.2 | 16.98 ± 12.4 | <0.05 | |
|
| ||||
| Spirometric values | FEV1 (L) | 1.31 ± 0.51 | 1.82 ± 0.73 | <0.05 |
| FEV1 % | 61.9 ± 29.9 | 70.9 ± 19.8 | ns | |
| FVC (L) | 2.51 ± 0.65 | 2.85 ± 0.91 | ns | |
| FVC % | 83.7 ± 20.9 | 83.2 ± 15.2 | ns | |
| FEV1/FVC | 52.7 ± 15.9 | 63.9 ± 13.6 | 0.01 | |
|
| ||||
| Ig (mg/dL) | IgA | 182 ± 74 | 237 ± 114 | ns |
| IgM | 309 ± 124 | 110 ± 53 | <0.01 | |
| IgG | 812 ± 198 | 920 ± 310 | ns | |
|
| ||||
| IgG subclass (mg/dL) | IgG1 | 472 ± 105 | 544 ± 226 | ns |
| IgG2 | 290 ± 128 | 302 ± 132 | ns | |
| IgG3 | 63 ± 30 | 74 ± 63 | ns | |
| IgG4 | 19 ± 17 | 26 ± 26 | ns | |